Brexpiprazole HCl( OPC 34712 dihydrochloride )

Catalog No. M22542 CAS No. 913612-38-1

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Product Name

Brexpiprazole HCl
Note

Research use only, not for human use.
Brief Description

Brexpiprazole is a new antipsychotic drug.
Description

Brexpiprazole is a new antipsychotic drug.
In Vitro

Brexpiprazole (0-1.0 μM, 4 days) potentiates NGF-induced neurite outgrowth in a dose-dependent manner in PC12 cells.
In Vivo

Brexpiprazole (0-0.1 mg/kg; p.o.; once) improves social recognition deficits in mice. Animal Model:Male C57BL/6NCrSlc mice, Dizocilpine (0.1 mg/kg) (HY-15084B) induced social recognition deficits Dosage:0.01, 0.03 and 0.1 mg/kg Administration:Oral administration, once Result:Significantly ameliorated Dizocilpine-induced social recognition deficits, without sedation or a reduction of exploratory behavior.
Synonyms

OPC 34712 dihydrochloride
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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1. Wen-Yu Hsu , Hsien-Yuan Lane , Chieh-Hsin Lin.Brexpiprazole for the treatment of schizophrenia.Expert Opin Pharmacother. 2017 Feb;18(2):217-223.

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